Prognostic impact of pancreatic margin status in the intraductal papillary mucinous neoplasms of the pancreas.

摘要: Background Intraductal papillary mucinous neoplasm (IPMN) of the pancreas often recurs after operative resection. The absolute risk and incidence recurrence, however, especially in remnant pancreas, is unknown. Methods We reviewed our 18-year experience 144 surgical cases IPMNs selected 103 benign IPMN carcinoma situ (CIS) for analysis clinicopathologic features long-term outcome recurrent disease, with particular emphasis on status cut margins pancreas. Results No patient died within 5 years. Recurrences were observed 9 cases: 4 (4.9%) among 81 (22.7%) 22 CIS. All recurrences considered as multicentric because none recurred at true resection margin previous pancreatic transection was normal or hyperplastic 64 patients, whereas adenoma detected 28 patients. presence had no influence outcome, recurrence diagnosed (7.8%) adenoma-negative patients 3 (10.7%) adenoma-positive Furthermore, both overall survival recurrence-free similar between 2 groups. Conclusion In CIS, a favorable prognosis can be expected irrespective surface, although follow-up adequate imaging studies recommended detection disease.