Effects of combretastatin A4 phosphate on endothelial cell morphology in vitro and relationship to tumour vascular targeting activity in vivo.

作者: David J. Chaplin , Michael R. L. Stratford , Borivoj Vojnovic , Rosalind J. Locke , Gillian M. Tozer

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关键词: PathologyCombretastatin A-4 phosphateCell biologyZD6126ColchicineEndothelial stem cellBiologyRed CellIn vivoConfluencyApoptosis

摘要: Background Combretastatin A4 Phosphate (CA4P) is a tubulin binding agent which causes rapid tumour vascular shutdown. It has anti-proliferative and apoptotic effects on dividing …

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