Selective aromatic chlorination of activated arenes with sodium chlorite, (salen)manganese(III) complex, and alumina in dichloromethane

摘要: The reaction of alkyl phenyl ethers with sodium chlorite in dichloromethane the presence a (salen)manganese(III) complex and alumina preloaded small amount water afforded monochlorination products unusually high para selectivities under mild conditions. NaClO2-based biphasic system can also be successfully used for regioselective substituted anisoles polymethoxybenzenes. Keywords: aromatic chlorination, aryl ethers, chlorite, complex, alumina.