One- and five-year follow-ups on blood pressure and renal function in kidney donors.

作者: Geir Mjoen , Karsten Midtvedt , Ingar Holme , Ole Øyen , Per Fauchald

DOI: 10.1111/J.1432-2277.2010.01148.X

关键词: SurgeryUrologyMean blood pressureDonationNephrectomyBlood pressureMedicineRenal functionProteinuriaKidneyRetrospective data

摘要: Summary It is considered safe to donate a kidney if internationally accepted medical criteria are fulfilled. However, some donors have encountered hypertension, proteinuria and impaired renal function after donation. The study was based on retrospective data 908 donors, donating in the period 1997–2007. Preoperative follow-up were collected from patient files Norwegian Living Donor Registry. Follow-up available for 665 at 1 year donation, 256 5 years We calculated estimated glomerular filtration rate (eGFR) using four variable Modification of Diet Renal Disease equation. At 1 prevalence hypertension 11.7% 27.1% respectively compared 2.6% before Proteinuria present 3.3% 1.6% 5 years. Mean eGFR 56.1 ± 10.8 ml/min/1.73 m² 61.0 ± 11.8 ml/min/1.73 m² blood pressure 122.5 ± 10.6/76.2 ± 7.5 mmHg donation (n = 908), 124.3 ± 14.2/77.9 ± 8.2 mmHg 1-year (n = 649) 127.2 ± 15.4/78.8 ± 8.3 mmHg 5-year follow-ups (n = 247). found no evidence further decline beyond initial decrement following nephrectomy.

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