Thrombocytopenia and platelet functional defects in pre-eclampsia: implications for regional anaesthesia.
作者： M. Schindler , S. Gatt , P. Isert , D. Morgans , A. Cheung
DOI: 10.1177/0310057X9001800202
关键词: Thromboxane B2 、 Platelet 、 Coagulopathy 、 Bleeding time 、 Internal medicine 、 Anesthesia 、 Platelet Factor 3 、 Fibrinolysis 、 Gastroenterology 、 Medicine 、 Preeclampsia 、 Prolonged bleeding time
摘要: A prospective, observational study of forty pre-eclamptic patients was conducted to confirm or refute reports a platelet functional defect superimposed on the consumptive thrombocytopenia pre-eclampsia. Investigations included count, in vivo function as assessed by Duke bleeding time, and vitro thromboxane B2 Platelet Factor 3 (PF 3). The overall incidence 15%. Prolonged time slightly decreased availability PF (evidence possible dysfunction) present 2.5% while 21% had evidence fibrinolysis with an elevated monoclonal D-dimer. In assessment suitability for regional blockade, count is essential. If between 50 100 x 10(9)/l indicated.
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