Response to vaccination with a commercial inactivated rabies vaccine in a captive colony of Brazilian free-tailed bats (Tadarida brasiliensis).
作者： Amy S. Turmelle , Louise C. Allen , Barbara A. Schmidt-French , Felix R. Jackson , Thomas H. Kunz
DOI: 10.1638/2008-0161.1
关键词: Immunity 、 Titer 、 Rabies vaccine 、 Rabies 、 Humoral immunity 、 Tadarida brasiliensis 、 Virology 、 Rabies virus 、 Vaccination 、 Biology
摘要: A captive colony of Brazilian free-tailed bats (Tadarida brasiliensis) was vaccinated with a commercial monovalent inactivated rabies virus (RABV) vaccine (RABVAC 1). Baseline neutralizing antibodies (VNA) and the response to vaccination were measured in 50 bats. Rabies VNA detected plasma 64% (27/42) that had been 1 yr prior, but only 19% (8/42) levels considered adequate. 63% (5/8) no record previous vaccination, suggesting natural RABV exposure before captivity. All demonstrated by 10 days postvaccination, baseline titer significantly predicted humoral vaccination. No adverse reactions or clinical signs infection observed during 6-mo observation period. Annual may maintain immunity against colonies
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