Discovery and characterization of natural products as novel indoleamine 2,3-dioxygenase 1 inhibitors through high-throughput screening
作者： Wei Guo , Sheng Yao , Pu Sun , Tian-biao Yang , Chun-ping Tang
DOI: 10.1038/S41401-019-0246-4
关键词: Biochemistry 、 Docking (molecular) 、 Indoleamine 2,3-dioxygenase 、 High-throughput screening 、 Chemistry 、 Enzyme 、 Non-competitive inhibition 、 Recombinant DNA 、 Uncompetitive inhibitor 、 Natural product
摘要: … b The effects of 79 natural products on the activity of IDO1 using a method based on Ehrlich’… Compared with the existing IDO1 inhibitors, the inhibitors identified in this study exhibited …
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