[Pregnancy and lactation-associated osteoporosis].

作者: M. Gehlen , A. D. Lazarescu , C. Hinz , B. Boncu , N. Schmidt

DOI: 10.1007/S00393-016-0259-Z

关键词: Depression (differential diagnoses)BisphosphonatePediatricsMedicineDiseasePostpartum depressionPregnancyLow back painMultimodal therapyOsteoporosis

摘要: Pregnancy and lactation-associated osteoporosis (PLO) is a rare form of osteoporosis, which occurs in the last trimester or postpartum. So far 100 cases have been published. The leading symptoms are severe low back pain less frequently hip pain. Many patients develop postpartum depression due to inability care for baby vertebral fractures. therapeutic decision has be made individually but teriparatid bisphosphonates seem best option. We report clinical course (16 years) 37-year-old patient with PLO, who suffered 6 There were physical limitations mental problems caused by disease. was treated multimodal therapy including physiotherapy psychotherapy given. time between onset diagnosis 5 months. No further fractures occurred following 16 years. condition significantly improved.

参考文章(10)
C. S. Kovacs, S. H. Ralston, Presentation and management of osteoporosis presenting in association with pregnancy or lactation. Osteoporosis International. ,vol. 26, pp. 2223- 2241 ,(2015) , 10.1007/S00198-015-3149-3
A. J. Phillips, S. J. Ostlere, R. Smith, Pregnancy-associated osteoporosis: does the skeleton recover? Osteoporosis International. ,vol. 11, pp. 449- 454 ,(2000) , 10.1007/S001980070113
Eun Yeong Choe, Je Eun Song, Kyeong Hye Park, Hannah Seok, Eun Jig Lee, Sung-Kil Lim, Yumie Rhee, Effect of teriparatide on pregnancy and lactation-associated osteoporosis with multiple vertebral fractures Journal of Bone and Mineral Metabolism. ,vol. 30, pp. 596- 601 ,(2012) , 10.1007/S00774-011-0334-0
Kurt Kroenke, Robert L Spitzer, Janet BW Williams, Bernd Löwe, An ultra-brief screening scale for anxiety and depression: The PHQ-4 Psychosomatics. ,vol. 50, pp. 613- 621 ,(2009) , 10.1176/APPI.PSY.50.6.613
G Raffaet�, Osteoporosis with vertebral fractures associated with pregnancy: two case reports. Clinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal Diseases. ,vol. 11, pp. 136- 138 ,(2014) , 10.11138/CCMBM/2014.11.2.136
L. Hellmeyer, P. Hadji, V. Ziller, U. Wagner, S. Schmidt, Knochenstoffwechsel in der Stillzeit Geburtshilfe Und Frauenheilkunde. ,vol. 64, pp. 1279- 1284 ,(2004) , 10.1055/S-2004-821030
Basak Ozcelik, Aykan Ozcelik, Mursel Debre, Postpartum depression co-occurring with lactation-related osteoporosis. Psychosomatics. ,vol. 50, pp. 155- 158 ,(2009) , 10.1176/APPI.PSY.50.2.155
S. M. O’Sullivan, A. B. Grey, R. Singh, I. R. Reid, Bisphosphonates in pregnancy and lactation-associated osteoporosis. Osteoporosis International. ,vol. 17, pp. 1008- 1012 ,(2006) , 10.1007/S00198-006-0112-3
Michael Pfeifer, Bettina Begerow, Helmut W. Minne, Effects of a new spinal orthosis on posture, trunk strength, and quality of life in women with postmenopausal osteoporosis: a randomized trial. American Journal of Physical Medicine & Rehabilitation. ,vol. 83, pp. 177- 186 ,(2004) , 10.1097/01.PHM.0000113403.16617.93
Lucía Sanz-Salvador, Miguel Ángel García-Pérez, Juan J Tarín, Antonio Cano, ENDOCRINOLOGY IN PREGNANCY: Bone metabolic changes during pregnancy: a period of vulnerability to osteoporosis and fracture European Journal of Endocrinology. ,vol. 172, ,(2014) , 10.1530/EJE-14-0424