Presentation and management of osteoporosis presenting in association with pregnancy or lactation.

摘要: In this review, we summarize our current understanding of the pathophysiology fragility fractures that occur for first time during pregnancy and lactation, provide guidance on appropriate investigations treatment strategies. Most affected women will have had no prior bone density reading, so extent loss may occurred or lactation is uncertain. During pregnancy, intestinal calcium absorption doubles in order to meet fetal demand calcium, but if maternal intake insufficient combined needs mother baby, skeleton undergo resorption third trimester. several hormonal changes, independent intake, program a 5–10 % trabecular mineral content milk. After weaning normally restored its strength. This physiological reproduction does not cause fractures; instead, who do fracture are more likely additional secondary causes fragility. Transient osteoporosis hip affect one both femoral heads it involves localized edema skeletal resorption. Case reports described use calcitonin, bisphosphonates, strontium ranelate, teriparatide, vertebroplasty, kyphoplasty treat post-partum vertebral fractures. However, need such treatments uncertain given progressive increase mass subsequently occurs most present with lactation.