Maternal Mineral and Bone Metabolism During Pregnancy, Lactation, and Post-Weaning Recovery

作者: Christopher S. Kovacs

DOI: 10.1152/PHYSREV.00027.2015

关键词:

摘要: During pregnancy and lactation, female physiology adapts to meet the added nutritional demands of fetuses neonates. An average full-term fetus contains ∼30 g calcium, 20 phosphorus, 0.8 magnesium. About 80% mineral is accreted during third trimester; calcium transfers at 300-350 mg/day final 6 wk. The neonate requires 200 mg daily from milk first mo, 120 second mo (additional comes solid foods). Calcium can be more than double triple these values, respectively, in women who nurse twins triplets. 25% dietary normally absorbed healthy adults. Average maternal intakes American Canadian are insufficient fetal neonatal requirements if normal efficiency intestinal absorption relied upon. However, several adaptations invoked for without requiring increased by mother. doubles, whereas lactation skeleton resorbed provide milk. This review addresses our current knowledge regarding skeletal homeostasis that occur pregnancy, post-weaning recovery. Also considered impacts have on biochemical hormonal parameters homeostasis, consequences long-term health, presentation management disorders bone metabolism.

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