Colistin inhibition of mannose-resistant haemagglutination by K88-positive and K99-positive escherichia coli strains. A preliminary report.

作者: H. Søgaard , J.L. Larsen , S. Christensen

DOI: 10.1016/S0174-3031(83)80084-5

关键词: BacteriaHemagglutinationMicrobiologyEscherichia coliColistinSerial dilutionMannoseStrain (chemistry)BiologyBacterial cell structure

摘要: Summary Two enteropathogenic E. coli strains isolated from a calf and piglet succumbed to diarrhoea were studied. The bovine strain carried K99-antigen the porcine was K88-positive. Both agglutinated pig erythrocytes in presence of D-mannose. In test bacterial cell density 3 × 10 9 per ml doubling dilutions hereof used. haemagglutination titres 16 128, respectively. When bacteria exposed Colistin before mixing with red cells, inhibited completely 1.0 0.5 μ g/mg Colistin. At concentration 0.25 g/ml (1/4–1/2 MIC's) lowered by factor 16–32.

参考文章(9)
Garth W. Jones, The Attachment of Bacteria to the Surfaces of Animal Cells Microbial Interactions. pp. 139- 176 ,(1977) , 10.1007/978-1-4615-9698-1_4
Barry I. Eisenstein, Itzhak Ofek, Edwin H. Beachey, Interference with the Mannose Binding and Epithelial Cell Adherence of Escherichia coli by Sublethal Concentrations of Streptomycin Journal of Clinical Investigation. ,vol. 63, pp. 1219- 1228 ,(1979) , 10.1172/JCI109417
K Vosbeck, H Mett, U Huber, J Bohn, M Petignat, Effects of low concentrations of antibiotics on Escherichia coli adhesion. Antimicrobial Agents and Chemotherapy. ,vol. 21, pp. 864- 869 ,(1982) , 10.1128/AAC.21.6.864
H W Moon, R E Isaacson, J Pohlenz, Mechanisms of association of enteropathogenic Escherichia coli with intestinal epithelium. The American Journal of Clinical Nutrition. ,vol. 32, pp. 119- 127 ,(1979) , 10.1093/AJCN/32.1.119
Ida �rskov, Frits �rskov, Significance of Surface Antigens in Relation to Enterotoxigenicity of E. coli Karger Publishers. pp. 134- 141 ,(1980) , 10.1159/000403256
David A. Sack, Donald C. Kaminsky, R. Bradley Sack, J. N. Itotia, Ray R. Arthur, Albert Z. Kapikian, Frits Ørskov, Ida Ørskov, Prophylactic Doxycycline for Travelers' Diarrhea New England Journal of Medicine. ,vol. 298, pp. 758- 763 ,(1978) , 10.1056/NEJM197804062981402
Roland F, Heelan J, Inhibition of Escherichia coli haemagglutinations by antibiotics Annales de microbiologie. pp. 33- 42 ,(1979)