Effects of low concentrations of antibiotics on Escherichia coli adhesion.

摘要: Bacterial adhesion to eukaryotic cells is thought represent an important factor in the pathogenesis of certain infectious diseases [6]. Agents interfering with process bacterial may therefore have beneficial prophylactic or therapeutic effects. Recent evidence indicates that antibiotics affect at low concentrations do not significantly influence growth [3, 7, 9]. We employed a tissue-culture model system [2, 9, 11] investigate subinhibitory effects on adhesion. Since biological relevance assays be criticized, we compared antibiotic our those seen other systems. The present report demonstrates some change adhesiveness Escherichia coli strains number different strain-specific manner. Although there was no absolute correlation between assay systems, one can generalize these large extent, and they correlate observations authors 6].