IMPROVING NUCLEIC ACID QUANTITATION BY COMPRESSING THE DYNAMIC RANGE OF HIGH-ABUNDANCE MOLECULES
作者： Cantor Charles R
DOI:
关键词: Chemistry 、 Dynamic range 、 Nucleic acid quantitation 、 Abundance (ecology) 、 Low copy number 、 Biochemistry 、 Nucleic acid sequence 、 Nucleic acid 、 Molecule
摘要: Described herein are products and processes for nucleic acid quantification, which in part useful detecting determining the nucleotide sequence of rare acids (i.e., low copy number acids) a sample. Such reducing dynamic range among different species.
lens.org 参考文章(8)
Christopher K. Raymond, John Castle, Christopher Armour, Nucleic acid amplification using non-random primers ,(2006)
Benjamin Schroeder, Gary P. Schroth, Caifu Chen, Methods for the enrichment of low-abundance polynucleotides ,(2003)
York Yuan-Yuan Zhu, Methods for identifying low-abundance polynucleotides and related compositions ,(2001)
Dirk Van Den Boom, Sebastian Boecker, Fragmentation-based methods and systems for sequence variation detection and discovery ,(2003)
Stephen B. Baylin, James G. Herman, Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids ,(1997)
Juan Yguerabide, Evangelina E. Yguerabide, David E. Kohne, Jeffrey T. Jackson, Analyte assay using particulate labels ,(1997)
Alexander Olek, Kurt Berlin, Highly sensitive method for the detection of cytosine methylation patterns ,(2002)
Cathy E. Lofton-Day, John K. Day, Discovery and diagnostic methods using 5-methylcytosine dna glycosylase ,(2003)