Quantification of CK20 gene and protein expression in colorectal cancer by RT-PCR and immunohistochemistry reveals inter- and intratumour heterogeneity.

作者: Silke Lassmann , Markus Bauer , Richie Soong , Joachim Schreglmann , Karim Tabiti

DOI: 10.1002/PATH.1196

关键词: Molecular pathologyColorectal cancerReverse transcription polymerase chain reactionPathologyReal-time polymerase chain reactionCytokeratinGene expressionBiologyImmunohistochemistryKeratin 20

摘要: … was detected by immunohistochemistry (IHC) in 60/63 (95.2… IHC in 32 cases. This was also true for selected heterogeneous tumour cells within individual cases. Both RT‐PCR and IHC …

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