Multi-omics in mesial temporal lobe epilepsy with hippocampal sclerosis: Clues into the underlying mechanisms leading to disease

作者: Iscia Lopes-Cendes , Mariana Martin , Danielle C.F. Bruno , Alexandre B Godoi , Amanda M. do Canto

DOI: 10.1016/J.SEIZURE.2021.03.002

关键词: Severe epilepsyMulti omicsEpilepsyHippocampal sclerosisLesionNeuroscienceDiseaseEpileptogenic lesionMesial temporal lobe epilepsyMedicine

摘要: … Furthermore, we will address studies about transcriptomics, … refractory MTLE+HS and animal models of the disorder. We … Thus, they combined RNA sequencing data, proteomic data, …

参考文章(227)
David Stellwagen, Robert C. Malenka, Synaptic scaling mediated by glial TNF-α Nature. ,vol. 440, pp. 1054- 1059 ,(2006) , 10.1038/NATURE04671
Neil J. Risch, Searching for genetic determinants in the new millennium Nature. ,vol. 405, pp. 847- 856 ,(2000) , 10.1038/35015718
R. Mark Wellard, Regula S. Briellmann, James W. Prichard, Ari Syngeniotis, Graeme D. Jackson, Myoinositol abnormalities in temporal lobe epilepsy. Epilepsia. ,vol. 44, pp. 815- 821 ,(2003) , 10.1046/J.1528-1157.2003.44102.X
Stefan H. Lelieveld, Malte Spielmann, Stefan Mundlos, Joris A. Veltman, Christian Gilissen, Comparison of Exome and Genome Sequencing Technologies for the Complete Capture of Protein-Coding Regions Human Mutation. ,vol. 36, pp. 815- 822 ,(2015) , 10.1002/HUMU.22813
Dennis Lal, Katharina Pernhorst, Karl Martin Klein, Philipp Reif, Rossana Tozzi, Mohammad R. Toliat, Georg Winterer, Bernd Neubauer, Peter Nürnberg, Felix Rosenow, Felicitas Becker, Holger Lerche, Wolfram S. Kunz, Mitja I. Kurki, Per Hoffmann, Albert J. Becker, Emilio Perucca, Federico Zara, Thomas Sander, Yvonne G. Weber, Extending the phenotypic spectrum of RBFOX1 deletions: Sporadic focal epilepsy Epilepsia. ,vol. 56, ,(2015) , 10.1111/EPI.13076
Ahmed Omran, Jing Peng, Ciliu Zhang, Qiu-Lian Xiang, Jinfeng Xue, Na Gan, Huimin Kong, Fei Yin, Interleukin-1β and microRNA-146a in an immature rat model and children with mesial temporal lobe epilepsy Epilepsia. ,vol. 53, pp. 1215- 1224 ,(2012) , 10.1111/J.1528-1167.2012.03540.X
J Urenjak, SR Williams, DG Gadian, M Noble, Proton nuclear magnetic resonance spectroscopy unambiguously identifies different neural cell types The Journal of Neuroscience. ,vol. 13, pp. 981- 989 ,(1993) , 10.1523/JNEUROSCI.13-03-00981.1993
Merab Kokaia, Seizure-induced neurogenesis in the adult brain. European Journal of Neuroscience. ,vol. 33, pp. 1133- 1138 ,(2011) , 10.1111/J.1460-9568.2011.07612.X
Noora Putkonen, Jyrki P. Kukkonen, Guiseppa Mudo, Jaana Putula, Natale Belluardo, Dan Lindholm, Laura Korhonen, Involvement of cyclin‐dependent kinase‐5 in the kainic acid‐mediated degeneration of glutamatergic synapses in the rat hippocampus European Journal of Neuroscience. ,vol. 34, pp. 1212- 1221 ,(2011) , 10.1111/J.1460-9568.2011.07858.X
Wagner G Horta, Eduardo Paradela, André Figueiredo, Isabella D’Andrea Meira, Valéria C Santa Rita Pereira, Cláudia C Rego, Raquel Oliveira, Maria Emilia C Andraus, Glenda C Borges de Lacerda, Polyana Moura, Jorge P Marcondes de Souza, Carmen Lucia A Paiva, Soniza V Alves-Leon, None, Genetic association study of the HLA class II alleles DRB1, DQA1, and DQB1 in patients with pharmacoresistant temporal lobe epilepsy associated with mesial hippocampal sclerosis Seizure-european Journal of Epilepsy. ,vol. 31, pp. 7- 11 ,(2015) , 10.1016/J.SEIZURE.2015.06.005