摘要: Nonostante i notevoli progressi delle tecniche di imaging, della chirurgia, radioterapia, chemioterapia e terapie biologiche, carcinomi dell’ipofaringe hanno ancora una cattiva prognosi. Questi sono quasi sempre diagnosticati in fase avanzata. Insorgono pazienti con lunga storia abuso tabacco alcol. Tale stile vita determina importanti comorbidita che compromettono la tolleranza al trattamento compliance alle combinate, si rendono spesso necessarie a causa dell’estensione locoregionale malattia dell’elevat frequenza metastasi distanza.
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