Circadian Disruption: Potential Implications in Inflammatory and Metabolic Diseases Associated With Alcohol

作者: Ali Keshavarzian , Christopher B Forsyth , Robin M Voigt

DOI:

关键词: Circadian rhythmImmune systemChronobiology DisordersEpigeneticsInflammationNeuroscienceBiologyFunction (biology)EpigenesisOrganism

摘要: Circadian rhythms are a prominent and critical feature of cells, tissues, organs, behavior that help an organism function most efficiently anticipate things such as food availability. Therefore, it is not surprising disrupted circadian rhythmicity, modern-day society, promotes the development and/or progression wide variety diseases, including inflammatory, metabolic, alcohol-associated disorders. This article will discuss influence interplay between alcohol consumption rhythmicity how rhythm disruption affects immune metabolism well potential epigenetic mechanisms may be contributing to this phenomenon.

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