Outcome and Prognosis of Patients With Chronic Fatigue vs Chronic Fatigue Syndrome

摘要: Background: There are few data on the natural history and prognosis of persons with chronic fatigue (CF) or CF syndrome (CFS). Therefore, we compared functional outcomes in patients each condition tested validity various prognostic indicators. Methods: Four hundred forty-five (89%) 498 consecutive referral were surveyed an average 1.5 years after initial evaluation. Data from evaluation used to predict outcomes. Results: Sixty-four percent all reported improvement, but only 2% complete resolution symptoms. Patients initially diagnosed as having CFS greater symptom severity lower level functioning at follow-up than did CF. Major depression predicted unemployment group. Older age, longer duration illness, a lifetime dysthymia less improvement Current for Conclusions: The case definition according Centers Disease Control Prevention identifies chronically fatigued poorer prognosis. In tertiary care setting, recovery is rare, common. Prognostic indicators vary two groups, coexistence suggests generally. (Arch Intern Med. 1995;155:2105-2110)