Acute motor neuropathy with antibodies to GM1 ganglioside

作者: N. A. Gregson , D. Jones , P. K. Thomas , H. J. Willison

DOI: 10.1007/BF00314652

关键词: Guillain-Barre syndromeAntibodyImmunologyPolyclonal antibodiesMedicineGangliosidePeripheral neuropathyConcomitantNeurologyAutoantibody

摘要: We describe a 52-year-old man who had an acute-onset purely motor neuropathy fulfilling the diagnostic criteria for Guillain-Barre syndrome, in whom virtually complete spontaneous recovery occurred by 1 year, and high titres of polyclonal serum antibody to GM1, GD1b, asialo-GM1 lacto-N-tetraose were detected. The titre IgM GM1 fell during course disease with concomitant rise IgG titre. This case adds widening spectrum associated anti-GM1 antibodies provides further evidence relationship between system disease.

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