Occurrence and Mechanism of Exocytosis in Adrenal Medulla and Sympathetic Nerve
作者： H. Winkler
DOI: 10.1007/978-3-642-46625-0_2
关键词: Adrenal medulla 、 Chromaffin cell 、 Internal medicine 、 Exocytosis 、 Organelle 、 Endocrinology 、 Chemistry 、 Extracellular 、 Secretion 、 Rostral ventrolateral medulla 、 Vesicle
摘要: Secretion by exocytosis—a term introduced de Duve (1963)—involves the fusion of membrane catecholamine-storing vesicles with that cell, followed discharge soluble contents this organelle directly into extracellular space. When first Handbook on Catecholamines (Blaschko and Muscholl 1972) was published, chapter secretion catecholamines (Smith Winkler already presented exocytosis as well established mechanism for adrenal medulla more tentatively also sympathetic nerves. In meantime many additional papers have been which confirmed extended concept (550 622 publications cited in review appeared after 1972). On other hand, molecular mechanisms involved are still a matter speculation.
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