Prevention of Allogeneic Fetal Rejection by Tryptophan Catabolism
作者： David H Munn , Min Zhou , John T Attwood , Igor Bondarev , Simon J Conway
DOI: 10.1126/SCIENCE.281.5380.1191
关键词: Immunology 、 T lymphocyte 、 Indoleamine 2,3-dioxygenase 、 Conceptus 、 Kynurenine pathway 、 Transgene 、 T cell 、 Biology 、 Cellular immunity 、 Immune tolerance
摘要: In 1953 Medawar pointed out that survival of the genetically disparate (allogeneic) mammalian conceptus contradicts the laws of tissue transplantation. Rapid T cell–induced rejection of …
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