Genomic analysis in nephrology--towards systems biology and systematic medicine?
作者： Matthias A. Neusser , Maja T. Lindenmeyer , Matthias Kretzler , Clemens D. Cohen
DOI: 10.1016/J.NEPHRO.2008.04.003
关键词: Pathology 、 Transcriptome 、 Nephrology 、 Histopathological analysis 、 Review analysis 、 Computational biology 、 Internal medicine 、 Disease 、 Genomics 、 Medicine 、 Transcriptome profiling 、 Systems biology
摘要: With the advent of transcriptome profiling techniques, an enormous amount data has been generated in field molecular nephrology. We will review analysis tools and challenges for genomic approaches present their application gene-expression studies on kidney biopsies. The findings this rapidly evolving may ultimately complement histopathological analysis, current diagnostic prognostic gold standard. Altogether, genomics bring nephrology one-step closer to a systematic understanding biological processes involved renal disease.
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