Brain microglia were activated in sporadic CJD but almost unchanged in fatal familial insomnia and G114V genetic CJD
作者： Qi Shi , Wu-Ling Xie , BaoYun Zhang , Li-Na Chen , Yin Xu
关键词: Variant cjd 、 Microglia 、 Disease 、 Kuru 、 Pathology 、 Sporadic CJD 、 Virology 、 Fatal familial insomnia 、 Medicine
摘要: Background Microglial activations have been described in different subtypes of human prion diseases such as sporadic Creutzfeldt-Jakob disease (CJD), variant CJD, Kuru and Gerstmann-Straussler-Scheinker (GSS). However, the situation microglia other genetic fatal familial insomnia (FFI) CJD remains less understood. The brain was evaluated comparatively between FFI, G114V sCJD cases study.
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