Inactivation of porcine epidemic diarrhea virus using heated water
作者： Michele M. Zentkovich , Sarah W. Nelson , Jason W. Stull , Jacqueline M. Nolting , Andrew S. Bowman
DOI: 10.1016/J.VAS.2016.09.001
关键词: Multiple time 、 Pathogen 、 Porcine epidemic diarrhea virus 、 Virology 、 Chemical disinfection 、 Microbiology 、 Nucleic acid 、 Biology
摘要: Porcine epidemic diarrhea virus (PEDV) is a very contagious swine pathogen that spreads easily via the fecal-oral route, notably from contaminated fomites. The present study investigated heated water as method for rapid thermal inactivation of PEDV. Cell-culture adapted PEDV was treated with at varying temperatures and viral titers were measured multiple time points post-treatment. Viable not recovered after ten second or longer treatment to ≥76 °C; however, nucleic acid detected in all samples regardless treatment. Hot decontamination could be considered settings where chemical disinfection impractical.
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