Spinal traction promotes molecular transportation in a simulated degenerative intervertebral disc model.

摘要: Study design Biomechanical experiment using an in situ porcine model. Objective To find the effect of traction treatment on annulus microstructure, molecular convection, and cell viability degraded discs. Summary background data Spinal is a conservative for disc disorders. The recognized biomechanical benefits include height recovery, foramen enlargement, intradiscal pressure reduction. However, influence transportation, discs has not been fully investigated. Methods A total 48 thoracic were dissected from 8 spines (140 kg, 6-month old) within 4 hours after killing them then divided into 3 groups: intact, without traction, with traction. Each was incubated whole-organ culture system subjected to diurnal loadings 7 days. Except intact group, 0.5 mL trypsin day 1 5-hour fatigue loading 2. From 6, half received 30-minute per (traction force: 20 kg; loading: unloading = 30 s: 10 s). By end incubation, inspected loss, (fluorescein sodium) intensity, viability. Results Collagen fibers crimped delaminated, whereas pores occluded fibrosus Molecular transportation decreased matrix degradation. With treatment, straightened collagen increased fibrosus, less occluded. Both increased, but level. Conclusion Traction effective enhancing nutrition supply promoting proliferation Level evidence N/A.