Effects of ketoprofen alone or in combination with local anesthesia during the castration of bull calves on plasma cortisol, immunological, and inflammatory responses.

作者: B. Earley , M. A. Crowe

DOI: 10.2527/2002.8041044X

关键词: KetoprofenAnesthesiaLocal anesthesiaPlasma cortisolInternal medicineCastrationSurgical castrationMedicineBurdizzoEndocrinologyBeef cattleHydrocortisone

摘要: To determine the effects of anti-in- flammatory ketoprofen, alone or with local anesthesia (LA) during castration on cortisol, immune, and acute phase responses, 40 Friesian calves (215 ± 3.5 kg) were assigned as follows: 1) control, 2) surgical (SURG), 3) SURG following ketoprofen (3 mg/kg BW i.v.; + K), 4) LA (9 mL 2% lidocaine hydrochloride to each testis; LA), 5) K (SURG K). Total cortisol response was greater (P < 0.05) in SURG, LA, than control not different between calves. The interval peak longer for either On d 3, KLH-induced interferon- γ production lower calves, whereas concanavalin A-induced in-

参考文章(34)
D. B. Faulkner, T. Eurell, W. J. Tranquilli, R. S. Ott, M. W. Ohl, G. F. Cmarik, G. Zinn, Performance and health of weanling bulls after butorphanol and xylazine administration at castration. Journal of Animal Science. ,vol. 70, pp. 2970- 2974 ,(1992) , 10.2527/1992.70102970X
R L Simmons, E Yunis, L J Greenberg, M S Slade, Immunodepression after major surgery in normal patients. Surgery. ,vol. 78, pp. 363- 372 ,(1975)
Philippe Pibarot, Emmanuelle Grisneaux, Sophie Cuvelliez, Diane Blais, Jacques Dupuis, Guy Beauregard, Jérôme Planté, Johanne Bouffard, Norbert H. Bonneau, Comparison of ketoprofen, oxymorphone hydrochloride, and butorphanol in the treatment of postoperative pain in dogs. Javma-journal of The American Veterinary Medical Association. ,vol. 211, pp. 438- 444 ,(1997)
A D Fisher, M A Crowe, E M O'Nualláin, M L Monaghan, J A Larkin, P O'Kiely, W J Enright, Effects of cortisol on in vitro interferon-gamma production, acute-phase proteins, growth, and feed intake in a calf castration model. Journal of Animal Science. ,vol. 75, pp. 1041- 1047 ,(1997) , 10.2527/1997.7541041X
P.R. WOOD, L.A. CORNER, P. PLACKETT, Development of a simple, rapid in vitro cellular assay for bovine tuberculosis based on the production of γ interferon. Research in Veterinary Science. ,vol. 49, pp. 46- 49 ,(1990) , 10.1016/S0034-5288(18)31044-0
C. C. Chase, R. E. Larsen, R. D. Randel, A. C. Hammond, E. L. Adams, Plasma cortisol and white blood cell responses in different breeds of bulls: a comparison of two methods of castration Journal of Animal Science. ,vol. 73, pp. 975- 980 ,(1995) , 10.2527/1995.734975X
A D Fisher, M A Crowe, M E Alonso de la Varga, W J Enright, Effect of castration method and the provision of local anesthesia on plasma cortisol, scrotal circumference, growth, and feed intake of bull calves. Journal of Animal Science. ,vol. 74, pp. 2336- 2343 ,(1996) , 10.2527/1996.74102336X
CM McMEEKAN, DJ MELLOR, KJ STAFFORD, RA BRUCE, RN WARD, NG GREGORY, Effects of local anaesthesia of 4 to 8 hours' duration on the acute cortisol response to scoop dehorning in calves. Australian Veterinary Journal. ,vol. 76, pp. 281- 285 ,(1998) , 10.1111/J.1751-0813.1998.TB10160.X
R. D. H. COHEN, B. D. KING, L. R. THOMAS, E. D. JANZEN, EFFICACY AND STRESS OF CHEMICAL VERSUS SURGICAL CASTRATION OF CATTLE Canadian Journal of Animal Science. ,vol. 70, pp. 1063- 1072 ,(1990) , 10.4141/CJAS90-129
N.J. Petrie, D.J. Mellor, K.J. Stafford, R.A. Bruce, R.N. Ward, Cortisol responses of calves to two methods of tail docking used with or without local anaesthetic. New Zealand Veterinary Journal. ,vol. 44, pp. 9- 14 ,(1996) , 10.1080/00480169.1996.35923