Cannabidiol, a Cannabis sativa constituent, inhibits cocaine-induced seizures in mice: Possible role of the mTOR pathway and reduction in glutamate release.
作者： Pedro H. Gobira , Luciano R. Vilela , Bruno D.C. Gonçalves , Rebeca P.M. Santos , Antonio C. de Oliveira
DOI: 10.1016/J.NEURO.2015.08.007
关键词: Pharmacology 、 Cannabinoid receptor type 2 、 Cannabidiol 、 Neurotoxicity 、 Anticonvulsant 、 AM251 、 Cocaine intoxication 、 Cannabinoid 、 Chemistry 、 Cannabinoid receptor
摘要: … that CBD protects against cocaine-induced seizures and … the duration of cocaine (75 mg/kg)-induced seizures in mice. The … cocaine increases glutamate release, whereas CBD …
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