High susceptibility of analbuminemic rats to gastric tumor induction by N-methyl-N'-nitro-N-nitrosoguanidine.
作者： Kenji Sugiyama , Sumi Nagase , Akihiko Maekawa , Yuzo Hayashi , Hiroshi Onodera
DOI: 10.20772/CANCERSCI1985.77.3_219
关键词: Chemistry 、 Oral administration 、 Analbuminemia 、 Gastric tumor 、 Stomach 、 Internal medicine 、 Albumin 、 Endocrinology 、 Carcinogen 、 Nitrosamine 、 Biochemistry 、 Microgram
摘要: Analbuminemic rats were found to be highly susceptible induction of gastric tumors by N-methyl-N'-nitro-N-nitrosoguanidine (67-83 micrograms/ml) given the in drinking water for 32 weeks. The sacrificed at experimental week 44. Gastric 12 17 analbuminemic (70%) and 8 21 normal (38%). Intestinal developed 7 (41%) 9 (42%) rats.
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