Method of producing retinal pigment epithelial cell

作者: Masanori Sawada , Masayo Takahashi , Kiyotoshi Sekiguchi

DOI:

关键词: Adherent CultureAnatomyEvaluation methodsLamininPigmentCell biologyRetinalInduced pluripotent stem cellChemistryRetinal pigment epithelial cell

摘要: Provided are a method of producing retinal pigment epithelial cells, with which the differentiation-induction efficiency cells from pluripotent stem can be improved and highly pure obtained in short time through simple operation; culture for stably grown cultured; toxicity/drug efficacy evaluation employing useful transplant therapy; disease therapeutic drug. The present invention pertains to including step adherent human using substrate coated laminin E8 fragments; production or by aforedescribed methods; drug containing cells.

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