作者: Amber Watts , Ryan W. Walters , Lesa Hoffman , Jonathan Templin
DOI: 10.1371/JOURNAL.PONE.0153898
关键词: Disease 、 Gerontology 、 Alzheimer's disease 、 Case-control study 、 Dementia 、 Physical activity 、 Cardiorespiratory fitness 、 Medicine 、 Cognitive decline 、 Population
摘要: Physical activity shows promise for protection against cognitive decline in older adults with and without Alzheimer’s disease (AD). To better understand barriers to adoption of physical this population, a clear understanding daily weekly patterns is needed. Most accelerometry studies report average over an entire wear period considering the potential importance variability activity. This study evaluated individual differences amount intra-individual determined whether these could be predicted by AD status, day wear, age, gender, education, cardiorespiratory capacity. was measured via (Actigraph GT3X+) one week 86 (n = 33 n 53, respectively). Mixed-effects location-scale models were estimated evaluate predict Results indicated that compared controls, participants averaged 21% less activity, but non-significantly greater variability. Women men similar amounts women significantly variable. The differed across days wear. Increased capacity associated Investigation provided insight into monitor cardiovascular All individuals regardless status equally consistent their which may have been due highly sedentary sample and/or early stage those AD. These results highlight value both