Regulation of angiogenesis by a non-canonical Wnt - Flt1 pathway in myeloid cells
作者： James A Stefater III , Ian Lewkowich , Sujata Rao , Giovanni Mariggi , April C Carpenter
DOI: 10.1038/NATURE10085
关键词: Wnt signaling pathway 、 WNT5A 、 Neovascularization 、 Endocrinology 、 Biology 、 Somatic cell 、 Internal medicine 、 Cell biology 、 Vascular endothelial growth factor 、 Angiogenesis 、 Signal transduction 、 Retina
摘要: Myeloid cells are a feature of most tissues. Here we show that during development, retinal myeloid cells (RMCs) produce Wnt ligands to regulate blood vessel branching. In the mouse …
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