The Role of Incretins in Glucose Homeostasis and Diabetes Treatment

作者: Wook Kim , Josephine M. Egan

DOI: 10.1124/PR.108.000604

关键词: Sitagliptin PhosphateDiabetes mellitusDipeptidyl peptidase-4IncretinEndocrinologyInternal medicineBiologySitagliptinExenatideGlucose homeostasisInsulin

摘要: … A lack of secretion of incretins or an increase in their clearance are not pathogenic factors in diabetes. However, in type 2 diabetes (T2DM), GIP no longer modulates glucose-dependent …

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