The influence of BCG immunisation on tuberculin reactivity and booster effect in adults in a country with a high prevalence of tuberculosis
作者： K. Hizel , I. Maral , R. Karakus , F. Aktas
DOI: 10.1111/J.1469-0691.2004.00970.X
关键词: Mycobacterium tuberculosis 、 BCG vaccine 、 Internal medicine 、 Medicine 、 Tuberculin Unit 、 Vaccination 、 Immunology 、 Tuberculosis 、 Tuberculin 、 Latent tuberculosis 、 Booster (rocketry)
摘要: The relationship of age and previous BCG vaccination with tuberculin skin test (TST) reactivity was investigated to assess the interpretation TST results in adult population Turkey, where there is a high prevalence tuberculosis routine programme. influences vaccine status on booster reaction were also evaluated. applied (5 units purified protein derivative intradermally) two healthy groups, namely 98 medical students 187 elderly people retirement home. considered positive if an induration > or = 10 mm diameter produced. Subjects (41 39 students) < retested 1 week later. There no significant difference between (59.1%) subjects (58.8%) respect response. No influence scars observed either group. effect seen more commonly elderly, but presence scar did not It concluded that response adults high-prevalence countries may be caused by latent rather than vaccination.
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