Tuberculin Skin Test and Boosted Reactions among Newly Employed Healthcare Workers: An Observational Study

摘要: Objective To evaluate the prevalence of and factors associated with latent tuberculosis infection (LTBI) based on tuberculin skin test (TST) to estimate boosted reaction rate among newly employed healthcare workers (HCWs). Design Newly HCWs between January 2010 July 2012 at Severance Hospital in South Korea were enrolled this study. A one-step TST was conducted before October 2011, a two-step after 2011. Results Of 2132 participants, 778 (36.5%) had positive results. Being older (odds ratio [OR] 1.10, 95% confidence interval [CI] 1.06–1.13, P<0.001), male (OR 1.78, CI 1.21–2.62, P = 0.003), rejoining hospital workforce 1.58, 1.04–2.40, 0.032), having previous history (TB) 18.21, 2.15–154.10, 0.008) during period, being 1.15, 1.10–1.21, P<0.001) period significantly TST. performed 556 HCWs, observed 79 (14.2%). The induration size first (5–9-mm group) only factor second TST. Conclusions The LTBI high. not low; therefore, use may be necessary for regular monitoring countries an intermediate TB burden high Bacillus Calmette-Guerin vaccination.