Cloning, expression, activity and folding studies of serine hydroxymethyltransferase: a target enzyme for cancer chemotherapy.

作者: Shipra Agrawal , Ajay Kumar , Vivek Srivastava , B.N. Mishra

DOI: 10.1159/000076737

关键词: Amino acidMetabolismBiochemistrySerine hydroxymethyltransferaseCancer chemotherapySequence homologyGeneticsCloningBiologyFolding (chemistry)Enzyme

摘要: … Animal systems have been observed to possess two isoforms of SHMT, whereas plant systems have been found to have several multiple forms, localized in mitochondria, chloroplast …

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