Cannabis and Cannabinoids: Pharmacology, Toxicology, and Therapeutic Potential

摘要: * About the Editors Contributors Foreword Preface Definitions and Explanations Part I: Botany, Taxonomy, Chemistry, History Chapter 1. Botany of Natural Cannabis Medicines Introduction Life Cycle Agricultural Field Production Vegetative Crop Resin Gland Development Origins Taxonomy Medical Today Tomorrow Conclusion 2. Cannabinoids Phytocannabinoids Synthetic Analogues Anandamide Congeners Receptor Antagonists 3. Chemical Constituents 4. in Western Medicine Before Birth Christ Classical Era Hashish Arabic World Hemp Central Europe European Eighteenth Century Nineteenth-Century The Positive Trend Holds True 1880-1900: Climax As a Twentieth An Comes to an End II: Pharmacology Pharmacokinetics 5. Effects on Psyche Behavior Nervous System Neurochemistry Circulatory Other Organ Systems Tolerance Drug Interactions Cannabinoid Actions 6. General Absorption Bioavailability Distribution Metabolism Excretion Plasma Levels versus Administration Route 7. Sites Mechanisms Action Endogenous Ligands Palmitylethanolamide Inhibitors Tissue Uptake or Types Receptors Concluding Discussion 8. Analgesia Pharmacological sativa Do Have Analgesic Activity? Pain Control Pathways Cellular Summary 9. Neuroprotectants Against Ischemia Presynaptic Calcium Channels Postsynaptic Regulator Influx NMDA Blockade Oxidants Neuroprotective Antioxidants 10. Possible Autoimmune Diseases III: Indications for THC 11. Review Therapeutic Hierarchy Surveys 12. Use Cannabis: Experience California Proposition 215 Usage 13. Anorexia Cachexia Cancer Patients AIDS Patients: Wasting Syndrome Cannabis, 9-THC, Cachexia/AIDS 14. Antiemetic Antiemetics Clinical Rationale Data Current Role 15. Therapy Disorders Their Treatments Theoretical Experimental Trail Case Histories 16. Migraine Its Symptoms Standard Treatment with Pertinent Value Place 17. Spasti