Vitamin D and atherosclerosis.
作者： Arthur R. Menezes , Marie C. Lamb , Carl J. Lavie , James J. DiNicolantonio
DOI: 10.1097/HCO.0000000000000108
关键词: Immunology 、 Disease 、 Insulin resistance 、 Dyslipidemia 、 vitamin D deficiency 、 Endothelial dysfunction 、 Vitamin D and neurology 、 Medicine 、 Immune system 、 Vitamin
摘要: Purpose of review To provide an overview the association between vitamin D deficiency and atherosclerosis. Recent findings Vitamin exerts protective effects on atherosclerosis through multiple mechanisms. It has been shown to protect against endothelial dysfunction, vascular smooth muscle cell proliferation migration, modulation immune system, as well inflammatory response. In addition, have systemic insulin resistance, dyslipidemia, hypertension. Summary is widely prevalent in United States worldwide. Although this fat-soluble usually associated with musculoskeletal disorder, it a wide range disease processes that include organ systems. Recently, there mounting evidence linking cardiovascular
uq.edu.au参考文章(78)
Andreas Tomaschitz, Stefan Pilz, Eberhard Ritz, Tanja Grammer, Christiane Drechsler, Bernhard O. Boehm, Winfried März, Independent association between 1,25-dihydroxyvitamin D, 25-hydroxyvitamin D and the renin-angiotensin system: The Ludwigshafen Risk and Cardiovascular Health (LURIC) study. Clinica Chimica Acta. ,vol. 411, pp. 1354- 1360 ,(2010) , 10.1016/J.CCA.2010.05.037
S Shimizu, T Fujita, S Shiozawa, K Shiozawa, 1α,25-dihydroxyvitamin D3 inhibits pokeweed mitogen-stimulated human B-cell activation: An analysis using serum-free culture conditions Immunology. ,vol. 56, pp. 161- 167 ,(1985)
C D Tsoukas, S C Manolagas, L J Deftos, D M Provvedini, 1 alpha,25-Dihydroxyvitamin D3-binding macromolecules in human B lymphocytes: effects on immunoglobulin production. Journal of Immunology. ,vol. 136, pp. 2734- 2740 ,(1986)
Y Shi, M Feletou, D D Ku, R Y K Man, P M Vanhoutte, The calcium ionophore A23187 induces endothelium-dependent contractions in femoral arteries from rats with streptozotocin-induced diabetes British Journal of Pharmacology. ,vol. 150, pp. 624- 632 ,(2007) , 10.1038/SJ.BJP.0706999
Ellen D. Burgess, Ralph G. Hawkins, Mamoru Watanabe, Interaction of 1,25-dihydroxyvitamin D and plasma renin activity in high renin essential hypertension. American Journal of Hypertension. ,vol. 3, pp. 903- 905 ,(1990) , 10.1093/AJH/3.12.903
R.A. Pierce, M.E. Kolodziej, W.C. Parks, 1,25-Dihydroxyvitamin D3 represses tropoelastin expression by a posttranscriptional mechanism. Journal of Biological Chemistry. ,vol. 267, pp. 11593- 11599 ,(1992) , 10.1016/S0021-9258(19)49952-3
Christopher S. R. Baker, Roger J. C. Hall, Thomas J. Evans, Ariela Pomerance, Jacques Maclouf, Christophe Creminon, Magdi H. Yacoub, Julia M. Polak, Cyclooxygenase-2 Is Widely Expressed in Atherosclerotic Lesions Affecting Native and Transplanted Human Coronary Arteries and Colocalizes With Inducible Nitric Oxide Synthase and Nitrotyrosine Particularly in Macrophages Arteriosclerosis, Thrombosis, and Vascular Biology. ,vol. 19, pp. 646- 655 ,(1999) , 10.1161/01.ATV.19.3.646
O. Equils, Y. Naiki, A. M. Shapiro, K. Michelsen, D. Lu, J. Adams, S. Jordan, 1,25‐Dihydroxyvitamin D3 inhibits lipopolysaccharide‐induced immune activation in human endothelial cells Clinical and Experimental Immunology. ,vol. 143, pp. 58- 64 ,(2006) , 10.1111/J.1365-2249.2005.02961.X
Dawn S. Milliner, Alan R. Zinsmeister, Ellin Lieberman, Benjamin Landing, Soft tissue calcification in pediatric patients with end-stage renal disease Kidney International. ,vol. 38, pp. 931- 936 ,(1990) , 10.1038/KI.1990.293
Hong-Jun Wang, Jun-Ping Cao, Jing-Kao Yu, Li-Cai Zhang, Zhong-Jian Jiang, Dian-Shuai Gao, Calbindin-D28K expression induced by glial cell line-derived neurotrophic factor in substantia nigra neurons dependent on PI3K/Akt/NF-κB signaling pathway European Journal of Pharmacology. ,vol. 595, pp. 7- 12 ,(2008) , 10.1016/J.EJPHAR.2008.07.044