Role of serum tumor markers CA 125 and CEA in non-small cell lung cancer.

作者: D Harpole , A T Skarin , R Salgia , E Pisick , A Elias

DOI:

关键词: Oncofetal antigenGastroenterologyLung cancerCA 15-3AdenocarcinomaCancerPathologyInternal medicineMedicineCarcinomaCarcinoembryonic antigenHistopathology

摘要: Background CA 125 and CEA are valuable serum tumor markers that can be used to monitor response therapy in patients with various solid tumors. Systemic studies of CA125 have not been evaluated lung cancer. In this study, we report the levels compared it newly diagnosed cancer analyzed these pre- post-therapy. Materials methods Two hundred sixteen non-small were evaluated. correlated stage histopathology. Results shown lower early disease as unresectable or metastatic disease. significantly higher among adenocarcinoma, while there was no statistically significant relationship between histology 125. There a difference dependent on size. Thirty-seven for responses chemotherapy responders more likely decreases CEA. Conclusion When abnormally elevated inpatients witlrlung cancer, useful indicators extent, clinical therapeutic marker, may potentially important prognostic value.

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