Tissue carcinoembryonic antigen, calcium, copper and iron levels in cancerous lung patients.
作者： Ahmed Khalifa Alshukaili , Nasar Yousuf Alwahaibi , Jokha Sultan Algharibi , Amna Salim Alshukaili
DOI: 10.3779/J.ISSN.1009-3419.2011.01.06
关键词:
摘要: Background and objective The expression of various trace elements markers in lung cancer is controversial. aim this study to evaluate the presence calcium (Ca), copper (Cu), iron (Fe) carcinoembryonic antigen (CEA) cancerous untreated tissues determine a possible association between these cancer. Methods Fourty-eight tissue blocks, from Sultan Qaboos University Hospital, Sultanate Oman, were studied. Fe, Ca, Cu, CEA demonstrated blocks using Perl's Prussian blue, Von Kossa's, modified rhodanine immunohistochemical staining methods, respectively. Results Twenty-three 48 specimens showed positive Fe staining, 2 Ca Cu was absent all specimens. 93.7% expressed varying degree positivity. 81.25% sections high CEA. Conclusion Tissue concentrations not elevated therefore cannot be considered as potential marker. Despite low sensitivity specificity previously reported, should marker evaluation cancer. DOI: 10.3779/j.issn.1009-3419.2011.01.06
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