Preparation, characterization, and evaluation of chitosan-based nanoparticles as CpG ODN carriers

作者: Febriana Catur Iswanti , Indah Nurulita , Samsuridjal Djauzi , Mohamad Sadikin , Arief Budi Witarto

DOI: 10.1080/13102818.2019.1578690

关键词: Low toxicityChitosanBiocompatibilityDrug deliveryToll-like receptorChemistryCpG OligodeoxynucleotideBiophysicsNanoparticleAntigen

摘要: Chitosan-based particles are desirable materials for drug delivery because of their muco-adhesiveness in tissues, biocompatibility, low toxicity and effectiveness antigen transport. It is still ...

参考文章(23)
Wen Fan, Wei Yan, Zushun Xu, Hong Ni, Formation mechanism of monodisperse, low molecular weight chitosan nanoparticles by ionic gelation technique Colloids and Surfaces B: Biointerfaces. ,vol. 90, pp. 21- 27 ,(2012) , 10.1016/J.COLSURFB.2011.09.042
Aditya Pattani, Vandana B. Patravale, Lata Panicker, Pravin D. Potdar, Immunological effects and membrane interactions of chitosan nanoparticles. Molecular Pharmaceutics. ,vol. 6, pp. 345- 352 ,(2009) , 10.1021/MP900004B
Suwarti Suwarti, Tomohiko Yamazaki, Chechetka Svetlana, Nobutaka Hanagata, Recognition of CpG oligodeoxynucleotides by human Toll-like receptor 9 and subsequent cytokine induction. Biochemical and Biophysical Research Communications. ,vol. 430, pp. 1234- 1239 ,(2013) , 10.1016/J.BBRC.2012.12.068
M. Schmidt, K. Anton, C. Nordhaus, C. Junghans, B. Wittig, M. Worm, Cytokine and Ig‐production by CG‐containing sequences with phosphorodiester backbone and dumbbell‐shape Allergy. ,vol. 61, pp. 56- 63 ,(2006) , 10.1111/J.1398-9995.2005.00908.X
Maryam Amidi, Stefan G. Romeijn, Gerrit Borchard, Hans E. Junginger, Wim E. Hennink, Wim Jiskoot, Preparation and characterization of protein-loaded N-trimethyl chitosan nanoparticles as nasal delivery system. Journal of Controlled Release. ,vol. 111, pp. 107- 116 ,(2006) , 10.1016/J.JCONREL.2005.11.014
Helene Jonassen, Anna-Lena Kjøniksen, Marianne Hiorth, Stability of chitosan nanoparticles cross-linked with tripolyphosphate Biomacromolecules. ,vol. 13, pp. 3747- 3756 ,(2012) , 10.1021/BM301207A
Worawan Boonyo, Hans E. Junginger, Neti Waranuch, Assadang Polnok, Tasana Pitaksuteepong, Chitosan and trimethyl chitosan chloride (TMC) as adjuvants for inducing immune responses to ovalbumin in mice following nasal administration Journal of Controlled Release. ,vol. 121, pp. 168- 175 ,(2007) , 10.1016/J.JCONREL.2007.05.025
Song Chen, Huijie Zhang, Shanmugavel Chinnathambi, Nobutaka Hanagata, Synthesis of novel chitosan-silica/CpG oligodeoxynucleotide nanohybrids with enhanced delivery efficiency. Materials Science and Engineering: C. ,vol. 33, pp. 3382- 3388 ,(2013) , 10.1016/J.MSEC.2013.04.017