Partitioning Behavior of Aromatic Components in Jet Fuel into Diverse Membrane-coated Fibers
作者： Ronald E. Baynes , Xin-Rui Xia , Beth M. Barlow , Jim E. Riviere
DOI: 10.1080/15287390701549146
关键词: Polydimethylsiloxane 、 Biological media 、 Occupational irritant contact dermatitis 、 Chromatography 、 Gas chromatography 、 Solvent 、 Mass spectrometry 、 Chemistry 、 Membrane 、 Jet fuel
摘要: Jet fuel components are known to partition into skin and produce occupational irritant contact dermatitis (OICD) potentially adverse systemic effects. The purpose of this study was determine how jet (1) from solvent mixtures diverse membrane-coated fibers (MCFs) (2) biological media MCFs predict tissue distribution. Three MCFs, polydimethylsiloxane (PDMS, lipophilic), polyacrylate (PA, polarizable), carbowax (CAR, polar), were selected simulate the physicochemical properties in vivo. Following an appropriate equilibrium time between MCF dosing solutions, injected directly a gas chromatograph/mass spectrometer (GC-MS) quantify amount that partitioned membrane. vehicles (water, 50% ethanol–water, albumin-containing solution) studied for components. more hydrophobic component, greater partitioning membranes across all ty...
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