Co-treatment of chlorpyrifos and lead induce serum lipid disorders in rats Alleviation by taurine
作者： Motunrayo G Akande , Yusuf O Aliu , Suleiman F Ambali , Joseph O Ayo
关键词: Oxidative stress 、 Lead acetate 、 Oral gavage 、 Endocrinology 、 Chlorpyrifos 、 Internal medicine 、 Distilled water 、 Median lethal dose 、 Malondialdehyde 、 Taurine 、 Chemistry
摘要: The aim of this study was to investigate the effects taurine (TA) on serum lipid profiles following chronic coadministration chlorpyrifos (CP) and lead acetate (Pb) in male Wistar rats. Fifty rats randomly distributed into five groups served as subjects. Distilled water (DW) given DW group, while soya oil (SO; 1 mL kg−1) SO group. TA group treated with (50 mg kg−1). CP + Pb administered sequentially (4.25 kg−1; 1/20th median lethal dose (LD50)) at 233.25 kg−1 (1/20th LD50), received kg−1), (233.25 sequentially. treatments were once daily by oral gavage for 16 weeks. euthanised, blood samples collected termination study. Sera obtained from analyzed total cholesterol, high-density lipoprotein triglycerides, malondialdehyde, also activities antioxi...
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sci-hub.se 参考文章(32)
AM Kammon, S Sodhi, HS Banga, NS Nagra, RS Brar, J Singh, Chlorpyrifos chronic toxicity in broilers and effect of vitamin C. Open veterinary journal. ,vol. 1, pp. 21- 27 ,(2011) , 10.4314/OVJ.V1I1
H.H. Draper, M. Hadley, MALONDIALDEHYDE DETERMINATION AS INDEX OF LIPID PEROXIDATION Methods in Enzymology. ,vol. 186, pp. 421- 431 ,(1990) , 10.1016/0076-6879(90)86135-I
R., Hepatoprotective Effect of Taurine Against Oxidative Stress Due to Methotrexate in Rat American Journal of Animal and Veterinary Sciences. ,vol. 6, pp. 187- 192 ,(2012) , 10.3844/AJAVSP.2011.187.192
Max W.S. Oliveira, Juliane B. Minotto, Marcos R. de Oliveira, Alfeu Zanotto-Filho, Guilherme A. Behr, Ricardo F. Rocha, José C.F. Moreira, Fábio Klamt, Scavenging and antioxidant potential of physiological taurine concentrations against different reactive oxygen/nitrogen species Pharmacological Reports. ,vol. 62, pp. 185- 193 ,(2010) , 10.1016/S1734-1140(10)70256-5
Mohamed M. Lasram, Alya Berrahal Annabi, Naziha El Elj, Slimen Selmi, Abdelaziz Kamoun, Saloua El-Fazaa, Najoua Gharbi, Metabolic disorders of acute exposure to malathion in adult Wistar rats. Journal of Hazardous Materials. ,vol. 163, pp. 1052- 1055 ,(2009) , 10.1016/J.JHAZMAT.2008.07.059
A.T. Anitha Nandhini, S.D. Balakrishnan, C.V. Anuradha, Taurine improves lipid profile in rats fed a high fructose-diet Nutrition Research. ,vol. 22, pp. 343- 354 ,(2002) , 10.1016/S0271-5317(01)00391-8
Al-Sayeda A. Newairy, Heba M. Abdou, Protective role of flax lignans against lead acetate induced oxidative damage and hyperlipidemia in rats. Food and Chemical Toxicology. ,vol. 47, pp. 813- 818 ,(2009) , 10.1016/J.FCT.2009.01.012
Nagat Aly, Kawther EL-Gendy, Fatma Mahmoud, Abdel Khalek El-Sebae, Protective effect of vitamin C against chlorpyrifos oxidative stress in male mice Pesticide Biochemistry and Physiology. ,vol. 97, pp. 7- 12 ,(2010) , 10.1016/J.PESTBP.2009.11.007
Ahmed E. Abdel Moneim, Mohamed A. Dkhil, Saleh Al-Quraishy, The protective effect of flaxseed oil on lead acetate-induced renal toxicity in rats. Journal of Hazardous Materials. ,vol. 194, pp. 250- 255 ,(2011) , 10.1016/J.JHAZMAT.2011.07.097
Takashi ITO, Junichi AZUMA, [Taurine is a possible anti-atherosclerotic agent]. Folia Pharmacologica Japonica. ,vol. 123, pp. 311- 317 ,(2004) , 10.1254/FPJ.123.311