Impact of donor age in donation after circulatory death liver transplantation: Is the cutoff "60" still of relevance?

摘要: Background Advanced donor age has been identified as risk factor, when combined with warm ischemia, e.g. in donation after circulatory death (DCD). In several countries DCD livers, older than 60 years are not considered suitable due to concerns related poor graft function and development of ischaemic cholangiopathy. We evaluate this study outcome liver transplantation using grafts from donors years. Methodology We analysed (n=315), comparing >60 (n=93) ≤60 (n=222) our centre between 2005 2015. Endpoints included complications, patient survival. Multivariate analysis was performed define further key factors that predicted inferior outcome. Results Donor at the cut-off failed stratify The rate vascular, biliary overall complications comparably low both cohorts median CCI 42,7 points, independent age. Secondly, BMI above a threshold 25 kg/m2 significantly impacted on survival, any age, while cold ischemia times were predictive for loss. Conclusion Older can be successfully used good long-term outcomes, limited. Additional is transmitted by an increased BMI, regardless This article protected copyright. All rights reserved.