Subtle clues to diagnosis by histochemistry. Histiocytosis X.

作者: Lutz-D. Leder

DOI: 10.1097/00000372-197900140-00015

关键词: MedicineDifferential diagnosisPathologyMalignant histiocytosisAcid phosphataseImmunohistochemistryGiant cellHistiocytosisCytologyPeripheral blood mononuclear cell

摘要: Characteristic mononuclear cells with distorted nuclei and abundant pale-staining cytoplasms together osteoclast-like giant are the cytologic hallmarks of histiocytosis X. The demonstration acid phosphatase within in paraffin-embedded sections is a valuable aid to diagnosis. histologic differential diagnosis X includes some allergic granulomas, Hodgkin's disease, myelomonocytic leukemia, mastocytosis, malignant histiocytosis. Some technical prerequisites for accurate considered briefly.

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