Access to Artemisinin-Combination Therapy (ACT) and other Anti-Malarials: National Policy and Markets in Sierra Leone

作者: John H. Amuasi , Graciela Diap , Samuel Blay Nguah , Patrick Karikari , Isaac Boakye

DOI: 10.1371/JOURNAL.PONE.0047733

关键词: Private sectorHealth policyPublic sectorSocioeconomicsMalariaRural areaGeographyPublic policyNational PolicySierra leone

摘要: Malaria remains the leading burden of disease in post-conflict Sierra Leone. To overcome challenge anti-malarial drug resistance and improve effective treatment, Leone adopted artemisinin-combination therapy artesunate-amodiaquine (AS+AQ) as first-line treatment for uncomplicated P. falciparum malaria. Other national policy anti-malarials include artemether-lumefantrine (AL) an alternative to AS+AQ, quinine artemether complicated malaria; sulphadoxine-pyrimethamine (SP) intermittent preventive (IPTp). This study was conducted evaluate access recommended anti-malarials. A cross-sectional survey 127 medicine outlets (public, private NGO) urban rural areas. The availability on day survey, median prices, affordability available non-policy were calculated. Anti-malarials stocked 79% all surveyed. AS+AQ widely public outlets; AL only NGO sectors. Quinine nearly two-thirds over one-third outlets. SP Non-policy predominantly sector offered free. Among sold at a cost, same price course (US$1.56), tablets (US$0.63), found both injection had cost US$0.31 US$0.47 sector, while compared US$ 0.63 sector. more affordable than two days’ worth wages

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