作者: Valyn S. Bahm , Robert Babilon , Kodumudi S. Balaji , Sharon F. Levy , Jason J. Wu
DOI:
关键词: Dermatology 、 Medicine 、 Dosing regimen 、 Actinic keratosis 、 Drug administration 、 Transdermal 、 Imiquimod 、 Safety profile 、 Dosing
摘要: Pharmaceutical formulations and methods for the topical or transdermal delivery of 1-isobutyl-1H-imidazo[4,5-c]-quinolin-4-amine 1-(2-methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine, i.e., imiquimod, to treat actinic keratosis with short durations therapy, than currently prescribed commercially available ALDARA 5% imiquimod cream, as now approved by U.S. Food & Drug Administration (“FDA”), are disclosed described. More specifically, lower dosage strength deliver an efficacious dose treating acceptable safety profile dosing regimens that more convenient patient use regimen (“FDA”) cream also