Method of treating actinic keratosis with 3.75% imiquimod cream

作者: Valyn S. Bahm , Robert Babilon , Kodumudi S. Balaji , Sharon F. Levy , Jason J. Wu

DOI:

关键词: DermatologyMedicineDosing regimenActinic keratosisDrug administrationTransdermalImiquimodSafety profileDosing

摘要: Pharmaceutical formulations and methods for the topical or transdermal delivery of 1-isobutyl-1H-imidazo[4,5-c]-quinolin-4-amine 1-(2-methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine, i.e., imiquimod, to treat actinic keratosis with short durations therapy, than currently prescribed commercially available ALDARA 5% imiquimod cream, as now approved by U.S. Food & Drug Administration (“FDA”), are disclosed described. More specifically, lower dosage strength deliver an efficacious dose treating acceptable safety profile dosing regimens that more convenient patient use regimen (“FDA”) cream also

参考文章(138)
Michael Shaffelburg, Treatment of actinic keratoses with sequential use of photodynamic therapy; and imiquimod 5% cream. Journal of Drugs in Dermatology. ,vol. 8, pp. 35- ,(2009)
Sandra Sacre, Brian M. Foxwell, Treatments for inflammatory arthritis ,(2008)
Norman M. Price, The treatment of actinic keratoses with a combination of 5-fluorouracil and imiquimod creams. Journal of Drugs in Dermatology. ,vol. 6, pp. 778- 781 ,(2007)
Berman B, Villa Am, Poochareon Vn, Novel dermatologic uses of the immune response modifier imiquimod 5% cream. Skin therapy letter. ,vol. 7, pp. 1- 6 ,(2002)
Girish S. Munavalli, Tze-Chiang Meng, Michael H. Gold, Joel L. Cohen, Combination therapy with low dosage strength imiquimod and photodynamic therapy to treat actinic keratosis ,(2012)
Patrick J. Roddy, Terri F. Busch, Janet A. Vallejo, Suzanne S. Leung, Immune response modifier formulations ,(2007)