作者: Ulla Nivukoski , Aini Bloigu , Risto Bloigu , Mauri Aalto , Tiina Laatikainen
DOI: 10.1016/J.ALCOHOL.2019.03.001
关键词: Alcohol intake 、 Population 、 Liver enzyme 、 Environmental health 、 Alcohol 、 Health problems 、 Harm reduction 、 Binge drinking 、 Analysis of variance 、 Medicine
摘要: Abstract Background While alcohol use is linked with a wide variety of health problems, the question whether differences in drinking patterns could yield different outcomes has remained unclear. Patients and methods We measured liver enzymes (ALT, GGT) from consumers or without binge population-based sample Finland, where binge-type common. Data on use, diet, body weight, lifestyle (smoking, coffee consumption, physical activity), status were collected 19225 subjects (9492 men, 9733 women), aged 25–74 years. The participants subsequently classified to subgroups, both according frequencies amounts regular intake (low-, medium-, high-risk drinking). Results quantity was roughly linearly related GGT ALT activities. ANOVA analyses trends frequency showed significant increase men (p Conclusions These results emphasize possible adverse consequences hepatic function even those low-risk overall consumption. pattern should be more systematically implicated clinical recommendations for reduction.