Coerulospinal influence on recurrent inhibition of spinal motonuclei innervating antagonistic hindleg muscles of the cat.
作者： S. J. Fung , O. Pompeiano , C. D. Barnes
DOI: 10.1007/BF01907550
关键词: Reflex 、 Disinhibition 、 Renshaw cell 、 Motor neuron 、 Central nervous system 、 Locus coeruleus 、 Neuroscience 、 Chemistry 、 Inhibitory postsynaptic potential 、 Neurotransmission
摘要: The locus coeruleus's (LC's) effect on recurrent inhibition of gastrocnemius-soleus (GS) and common peroneal (CP) monosynaptic reflexes (MSRs) was demonstrated to exceed the concomitant facilitation, indicating independency LC's disinhibition facilitation measures in this study. In contrast, correlated closely with recurrently inhibited MSRs. phenomenon also accompanied by progressive delay diminution Renshaw cell field potential. Hence, recovery MSRs probably due, part at least, related activity. Furthermore, site-specific, discordant changes GS, compared CP MSRs, as revealed tracking studies imply that representations these antagonistic motonuclei may occupy different LC loci. Accordingly, nonuniform be due activation discrete aggregates neurons which are responsible predominantly controlling inhibitory pathway belonging one or other motonuclei. These findings support a differential control activity, releasing motoneurons for Ia synaptic transmission — disinhibitory process is crucial independent circuit antagonistics extensor flexor motoneurons.
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