作者: David L. Thomas
DOI: 10.1001/ARCHINTE.1993.00410140095011
关键词: Virology 、 Hepatitis 、 Medicine 、 Vaccination 、 Hepatitis B virus 、 Viral hepatitis 、 Hepatitis C 、 Hepatitis B 、 Internal medicine 、 Health care 、 Hepatitis C virus
摘要: Background: Health care personnel are at increased risk of occupational acquisition hepatitis B virus (HBV) infection. While effective vaccination for HBV is widely available, the prevalence and vaccine acceptance in hospital have not been recently assessed. In addition, C (HCV) a newly recognized cause parenterally acquired hepatitis, HCV transmission to health remains unclear. Methods: From April December 1991, The Johns Hopkins Hospital, Baltimore, Md, were offered anonymous testing asked complete confidential questionnaire. Serum samples tested surface antigen antibodies core antigen, HCV. Seroprevalence rates compared with those detected local blood donors during same year. Results: Antibodies found 59 (6.2%) 943 workers 1879 (1.8%) 104 239 ( P =.10). Infection was associated age (≥33 years) =.02), 10 or more years clinical employment =.003), lack Conclusion: These data suggest that infection Hospital similar observed donors, may be efficiently transmitted than setting. Efforts vaccinate against should vigorously pursued since 23% remain unvaccinated after 9 availability. Arch Intern Med. 1993;153:1705-1712)