Prostaglandin synthetase inhibitors and dysmenorrhea. A survey and personal clinical experience.

摘要: . A survey of earlier published studies on treatment dysmenorrhea with prostaglandin synthetase inhibitors is given and personal clinical experiences are presented. The time when should start in relation to the onset bleeding also discussed. A English Scandinavian literature yielded 532 patients. Pain relief was experienced 64 100 per cent patients these studies. incidence side-effects has generally been low but a few high reported. In current study 34 primary completed double-blind, placebo controlled naproxen. were treated for two cycles, 16 naproxen 18 placebo. mean score indicated “slight good” pain group “no alleviation” group. difference statistically significant (p = 0.003). Supplementary medication much more used compared 0.01). In no change whatsoever demonstrated alleviation interference every-day life, whereas there improvement No major side-effect registered. Thus none subjects withdrew from study.